The tail pigmentation pattern of C57BL/6J mice affects nociception/pain quantification in the tail flick test
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Evaluation of the analgesic effect of Mellissa officinalis extract by tail-flick test in mice
Bibliographical studies have been done on plants that are used as analgesics in traditional medicine, and Mellissa officinalis or Lemon Balm (LB) that there are some evidence indicating for its application as analgesics or its probable analgesic effect was selected for evaluation of analgesic effect by tail-flick test in mice. After scientific identification, the leaves and flowered branches ...
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in traditional medicine,some plants have been used as analysics.the aim of this investigation was to evaluate the analgesic effect of two plants,piper nigrum and Zingiber officinale that are used traditionally to relieve headache,rheumatic arthritis,and toothache.for this purpose the methanolic extract of zingiber and piper nigrum,in different doses,were injected intraperitonealy to mice and t...
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The development of combination therapy is a coherent approach in severe pain treatment. The present study investigated the antinociceptive effect of pregabalin alone and in combination with tramadol in acute pain modeling. Therefore, three groups of male mice received either pregabalin (1 to 400 mg/Kg), tramadol (10 to 80 mg/Kg) or their combination intraperitoneally. Then latency time, maximum...
متن کاملthe role of nmdars ligands on antinociceptive effects of pregabalin in the tail flick test
conclusions our findings support the role of nmdars in pregabalin antinociception, because the nmdar agonist, unlike the antagonist, decreased the antinociceptive effect of pregabalin, even if tail flick is not an adequate pain assessment method in this regard. background pregabalin as a new anticonvulsant has been used in different pain treatments. objectives the aim of this study was to inves...
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The development of combination therapy is a coherent approach in severe pain treatment. The present study investigated the antinociceptive effect of pregabalin alone and in combination with tramadol in acute pain modeling. Therefore, three groups of male mice received either pregabalin (1 to 400 mg/Kg), tramadol (10 to 80 mg/Kg) or their combination intraperitoneally. Then latency time, maximum...
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ژورنال
عنوان ژورنال: European Journal of Pain
سال: 2009
ISSN: 1090-3801
DOI: 10.1016/j.ejpain.2008.07.012